I upgraded from 4.2.8 to 4.4.10 and ever since then my zabbix server shows up after few hours of usage that its lost connection to all my clients. I have increased my max connections from 600 too 1000. Currently using 572. The server service is running and so is mariadb but it just stops responding to my clients and shows that everything is down. Sometime i reboot the server and it comes up ok other times i have to restore from backup. spec is on a esxi vm 24 cores, 48G mem. Anyone have any ideas why this is now happening?