Zabbix agent on Zabbix server is unreachable

[TSOMMoore]

I get "Zabbix agent on Zabbix server is unreachable for 5 minutes".
I have rebooted the Zabbix appliance and this is only happening on the Zabbix server.
The agent on all other host are working fine.

I am not a Linux guy so I am not sure how/where to troubleshoot.

[acropia]

This problems can have lots of different causes.

Try to check the following:

1. Is the Zabbix Server allowed to connect to Agent in zabbix_agentd.conf?
2. Is Zabbix Agent running? (systemctl status, or ps -A)
3. What is your OS? Do you have SELinux enabled?

[TSOMMoore]

Found the issue.
The IP address of the Zabbix server was changed from the default 127.0.0.1 address to the nic's ip address.
The conf file was set to use 127.0.01.
Thanks acropia, I found this while looking into suggestion number 1