Unable to connect to server

[sh_aslani]

Hello,
I read almost every thing about this problem, we have a zabbix server and 3 zabbix proxy with oracle database on backend, on one of zabbix proxy we got these logs:

Unable to connect to server [x.x.x46]:10051 [cannot connect to [[x.x.x.46]:10051]: [4] interrupted system call]

and some times:
Unable to connect to server [x.x.x46]:10051 [cannot connect to [[x.x.x.46]:10051]: [110] connection timed out]
Connection restored

another error that we have got:

[Z3005] query failed: [-1] ORA-03113: end-of-file on communication channel

2.

when I run telnet from proxy to server on port 10051 ,it is established
when I run telnet from proxy to database on it's port ,it is established
when I run telnet from server to proxy on port 10051 ,it is established


I don't have any packet loss on pinging from proxy to server and my average time is 2.958 and some time less.
this problem caused the get items stick in queue
If this is a network problem, how I can find out? what other reasons could cause this problem?
Sorry for my poor English

Best Regards

[Atoudam]

did you get a resolve to this issue? i also have this problem