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Since this graph does not tell us much, I would suggest to find the cause of the problem by looking into Zabbix server metrics.
For example, top tool might be useful to investigate what is causing such a load.
You might want to check the load metrics for 10 mins by executing: top -b -d 10 -n 60 > top_output.txt
Additionally, you might want to increase the debug level to at least 4 to check if there are any problems on server side, but the first step would be to see the origin of the CPU load (as above).
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