This page covers potential issues that could arise during installation of Zabbix
Zabbix frontend includes .htaccess files that limit access to directories api, conf and include. Since Apache 2.4 introduced a new access control syntax, running versions of Zabbix 2.2.1 and older might cause the following error to appear in the Apache error logs:
Using the outdated syntax in the Apache configuration files might prevent Apache from starting at all. To solve this problem either upgrade to Zabbix 2.2.2 or enable the Apache mod_access_compat module.
See Apache documentation for details.